Posted by drinda_h on August 13, 2008, 8:34 am, in reply to "How do you get MDS?"
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the blood is synthesized in the bone marrow of the long bones.
in MDS (Myelo-Dysplastic Syndrome), the bone marrow undergoes FIBROSIS i.e. replacement of blood elements with fibrous tissue that are not functional so the bone marrow does not produce blood any more.
As why the bone marrow become fibrosed, many theories, one of them is the megakaryoblast ( that is responsible for synthesis of platelets) will secret some factors that enhances the producton of collagen causing fibrosis.
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